From my very limited experience, I have found large tanks are a trade off.
Large tanks provide a much larger volume of water to have stability in parameters. If anything goes wrong, you can fix it before ti cause a lot of harm. Also, water changes can be much fewer.
However for me, it also meant much slower breeding. I *think* that is because the shrimp have a problem finding who molted in such a vast area.
In fact, I just tore down a 20g neo tank to put them back in a 10g, because breeding slowed down to about a 1/4 of what it was for as few shrimp I had in there.
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I wonder if you could have the best of all worlds? Sure, you could use a sump, however by using a divider with water flow- you keep the param stability, while containing the area for better breeding?